Ashwagandha 35 features Shoden^®, a purified extract of the leaves and roots of the ashwagandha plant that has been standardized to an industry-leading concentration of 35% withanolide glycosides. Shoden has been researched for its effects in helping the body adapt to physical and mental stressors and supporting the restoration of sleep quality.

Clinical Applications » Supports a Healthy Stress Response* » Supports Restful Sleep

Shoden® Ashwagandha Extract Shoden is an extract derived from the leaves and roots of the ashwagandha plant. This multi-patented ashwagandha extract is distinguished by its industry-leading concentration of 35% withanolide glycosides. Shoden has been clinically studied for its adaptogenic role in the stress response and for support of a more restful night sleep. Additionally, studies designed specifically to assess the safety of Shoden resulted in no adverse or toxic effects. XYMOGEN’s Ashwagandha 35 contains 240 mg of Shoden per the two-capsule daily dose.

Ashwagandha (Withania somnifera) is classified as an “adaptogenic” herb, indicating an ability to support how the body physiologically adapts. In the Ayurvedic tradition, ashwagandha is considered a rasayana, meaning it is used as a rejuvenator to achieve homeostasis, build vitality, and slow degenerative- and senescence-related processes. For thousands of years, ashwagandha has been used to help support ailments ranging from musculoskeletal conditions to sleep issues. It is widely used today for restoring physical and mental energy while balancing the effects of daily stress. Ashwagandha contains a wide range of biologically active chemical constituents collectively known as with anolides. Although the exact mechanism of action for a projected effect on stress response has yet to be elicited, ashwagandha extract appears to ease stress-induced increases of plasma corticosterone, lactic acid in the blood, and blood urea nitrogen. Due to the positive association of steroid hormones with general well-being and quality of life and the fact that cortisol is associated with stress, the influence of ashwagandha on these hormones has also been studied. A systematic review assessing the effects of ashwagandha for anxiety and stress response included five randomized controlled human trials. An analysis of results indicated that ashwagandha intervention resulted in greater score improvements than placebo in outcomes shown on anxiety or stress scales, with no observed adverse events